I recently listened to the following two podcasts and found them worth recommending:

• Distributing the Future (DTF 05-22-2006):  The middile interview with Brad Fitzpatrick of LiveJournal and Six Apart is very interesting from both a systems integration standpoint and from a software developer’s perspective.
  
• FLOSS Weekly #6: With Larry Augustin who started VA Linux and now has a host of open source enterprise solutions in a portfolio he helps foster.